Chronic kidney disease (CKD) What is chronic kidney disease? Chronic kidney disease (CKD) is a slow decline in your kidney function, generally occurring over a time period of greater than three months. Throughout the day, as you're eating, drinking, and exercising, your body engages in numerous metabolic processes. These processes create waste that must be cleared from your blood, and your kidneys are the organs responsible for this task. The kidneys clear waste and toxins from your blood, and these wastes and toxins exit your body in the form of urine. In essence, the kidneys make urine.
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